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Genetics

PGT is a laboratory test with limits, not a healthy-baby guarantee

If you add PGT because a website made it sound mandatory, read this first. If you have a known single-gene condition or a translocation, read it twice.

PGT-A

Preimplantation genetic testing for aneuploidy

Counts chromosomes in a trophectoderm biopsy to look for missing or extra chromosomes (aneuploidy). It is a screening test on a sample of cells, not a diagnosis of the whole embryo and not a guarantee of a healthy child.

PGT-M

Preimplantation genetic testing for monogenic conditions

Looks for a specific inherited gene variant when the indication is known (for example a family mutation). Often requires probe or workup development before the IVF cycle. This is not the same test as PGT-A.

PGT-SR

Preimplantation genetic testing for structural rearrangements

Used when a parent carries a translocation or other structural chromosome rearrangement. Requires a genetics workup so the laboratory can interpret that family’s rearrangement.

How testing sits on the IVF timeline

  1. 01

    Indication and counseling

    Age, recurrent miscarriage, prior aneuploid results, a known single-gene condition, or a structural rearrangement may be reasons to discuss PGT. Counseling should include what the test cannot do.

  2. 02

    IVF to blastocyst

    PGT requires IVF, culture to a stage where biopsy is possible, and usually freeze-all. It is not an add-on to IUI.

  3. 03

    Trophectoderm biopsy

    Embryologists remove a small number of cells from the trophectoderm, the lineage that becomes placenta, not the inner cell mass.

  4. 04

    Shipment and analysis

    The sample may be analyzed in-house or sent to an outside genetics laboratory. Ask which lab, which platform, and the stated turnaround.

  5. 05

    Report and transfer plan

    Results are used to decide which embryo, if any, to thaw. Mosaic, no-result, and discordant findings need a conversation, not a marketing slogan.

What results mean

  • A laboratory classification of the biopsied cells according to the test ordered.
  • Information that may change which embryo is selected for transfer, or whether any embryo is selected.
  • For PGT-M/SR, information tied to a specific genetic indication after proper workup.

What results do not mean

  • A guarantee of implantation, pregnancy, or live birth.
  • A guarantee of a healthy child. Many conditions are not tested.
  • A complete picture of every cell in the embryo. Mosaicism and sampling limits exist.
  • A substitute for prenatal testing if you become pregnant.
  • Proof that untested or “abnormal” embryos could never have resulted in a birth — the literature is more nuanced than clinic brochures.

Biopsy, shipment, and extra cost

Fertilite lists PGT at $2,500 plus $250 per biopsied embryo. Ask whether analysis is at an outside genetics laboratory, the turnaround, and who pays if a sample fails. PGT-M often needs probe or workup development before the cycle; that is a separate timeline and fee.

Freeze-all is the usual pattern: biopsy, vitrify, wait for the report, then a later transfer trip. That extra visit is part of the true cost.

  1. 1. Fertilite published package pricesIVF/ICSI, IUI, and PGT package figures as listed by the clinic. Prices may be adjusted to the Mexican-peso exchange rate and can change.
  2. 2. ASRM committee opinion on PGT-APGT-A can identify chromosomal aneuploidy. It does not guarantee implantation, pregnancy, or a healthy child, and it has recognized limitations.

Start

If this already feels clearer, the next step is a plan — not a booking.

A coordinator can map testing, monitoring, travel, and an itemized quote to your actual records. You do not need to decide on IVF to have that conversation.

Contact

Talk to a coordinator, not a chatbot

Coordinators typically reply during clinic hours. If you write overnight from the U.S., expect a response the next business morning, Pacific Time.

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